Allyl bromide → 1-Allyl-4-(3-Chloro-5-trifluoromethyl-phenyl)-piperazine

HRID 584082Notes

Reaction equation

HRID 584082 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.[CH2:18](Br)[CH:19]=[CH2:20]>>[CH2:20]([N:15]1[CH2:16][CH2:17][N:12]([C:4]2[CH:5]=[C:6]([C:8]([F:10])([F:11])[F:9])[CH:7]=[C:2]([Cl:1])[CH:3]=2)[CH2:13][CH2:14]1)[CH:19]=[CH2:18]

Participants

3

Reactant 2

HCID 7841Allyl bromideHCID 223451951-(3-Chloro-5-(trifluoromethyl)phenyl)piperazine

Product 1

HCID 223451741-Allyl-4-(3-Chloro-5-trifluoromethyl-phenyl)-piperazine

Procedure

Beginning with 1-(3-Chloro-5-trifluoromethyl-phenyl)-piperazine and allylbromide, the title compound was recovered by the procedure described in Example 2. MS m/z (rel. intensity, 70 eV)) 305 (M+, 7), 96 (57), 69 (bp), 68 (48), 56 (69).

Workup

  1. customthe title compound was recovered by the procedure

Sources & evidence

ORD record
ord-1aca4e8ade364f429cf7367ef3e51d79
Source dataset
uspto-grants-2005_08
Patent number
US06924374B2

Reaction notes

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