HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → 1-(3-Chloro-5-(trifluoromethyl)phenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | 1,3-Dichloro-5-(trifluoromethyl)benzene | HCID 35361 | — |
| Product | 1-(3-Chloro-5-(trifluoromethyl)phenyl)piperazine | HCID 22345195 | 52.1% |
Reaction Steps
Beginning with 3,5-dichlorobenzotrifluoride (500 mg, 2.32 mmol) and piperazine (1 g, 11.6 mmol), 320 mg of the title compound was recovered by the procedure described in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06924374B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-4f196782448f469e8575e99e3ce0db68 |
| Source note | uspto-grants-2005_08 |