HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-2-iodo-4-(trifluoromethyl)benzene → 4-(2-Chloro-5-trifluoromethyl-phenyl)-1-propyl-piperidin-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-2-iodo-4-(trifluoromethyl)benzene | HCID 69596 | — |
| Reactant | 1-Propyl-4-piperidone | HCID 90006 | — |
| Product | 4-(2-Chloro-5-trifluoromethyl-phenyl)-1-propyl-piperidin-4-ol | HCID 22345161 | — |
Reaction Steps
Beginning with 4-chloro-3-iodobenzotrifluoride and 1-propyl-4-piperidone, the titled compound was recovered by the procedure described in Preparation 4, MS m/z (rel. intensity, 70 eV)) 321 (M+, 8), 294 (38), 292, (bp), 274 (52), 56 (35).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06924374B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-ecee86ef583740cc81a6ced5b0fbbf50 |
| Source note | uspto-grants-2005_08 |