HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 584124Generated: October 25, 2026
Succinic anhydride → 3-[3-(4-Methylsulfanyl-phenyl)-[1,2,4]oxadiazol-5-yl]-propionic acid
https://huagongshe.com/reaction/584124
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Succinic anhydride | HCID 7922 | — |
| Reactant | HCID 178503197 | HCID 178503197 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-[3-(4-Methylsulfanyl-phenyl)-[1,2,4]oxadiazol-5-yl]-propionic acid | HCID 17122273 | — |
Reaction Steps
Succinic anhydride (112 mg, 1.12 mmol) and N-hydroxy-4-methylsulfanyl-benzamidine (203 mg, 1.12 mmol) were dissolved in 2.0 mL of DMF and heated at 120° C. overnight. The cooled solution was evaporated and dried to give 3-[3-(4-methylsulfanyl-phenyl)-[1,2,4]oxadiazol-5-yl]-propionic acid which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06924284B2 |
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| Source dataset | uspto-grants-2005_08 |
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| ORD ID | ord-1c92a610d92b49ddaf94ad9316aee7bc |
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| Source note | uspto-grants-2005_08 |
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