HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 22343030, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | 4-(3-amino-propylamino)-2H-phthalazin-1-one | HCID 11148674 | — |
| Reactant | HCID 22343257 | HCID 22343257 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22343030 | HCID 22343030 | — |
Reaction Steps
3-[5-(4-Methoxy-phenyl)-isoxazol-3-yl]-propionic acid (124 mg, 0.50 mmol) and 4-(3-amino-propylamino)-2H-phthalazin-1-one (100 mg, 0.46 mmol) were dissolved in DMF (2 mL) and treated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (95 mg, 0.50 mmol) and triethylamine (76 mg, 0.75 mmol). 3-[5-(4-Methoxy-phenyl)-isoxazol-3-yl]-N-[3-(4-oxo-3,4-dihydro-phthalazin-1-ylamino)-propyl]-propionamide was isolated by preparative RPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06924284B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-0a7cd6364b1b46d08160dd729e916c74 |
| Source note | uspto-grants-2005_08 |