HCID 178425642, compound → HCID 178481840, compound

HRID 584133Notes

Reaction equation

HRID 584133 reaction equation
ONC([C:5]1[CH:6]=[C:7]([NH:10][C:11](=[O:17])[O:12][C:13]([CH3:16])([CH3:15])[CH3:14])SC=1)=N.ONC(C1N(COCC[Si](C)(C)C)C=NC=1[NH:35][C:36](=O)OC(C)(C)C)=N.[OH:43][NH:44]C(C1N=CN(COCC[Si](C)(C)C)C=1NC(=O)OC(C)(C)C)=N.O[NH:69][C:70](C1C(C)=NOC=1NC(=O)OC(C)(C)C)=N.O[NH:87]C(C1C=C(NC(=O)OC(C)(C)C)C=CC=1)=N.FC1C=C(C=CC=1C)C(NO)=N.CC1SC=CC=1C(NO)=N.C(C1SC=CC=1C(NO)=N)C.C(S(NC1SC=C(C(NO)=N)C=1)(=O)=O)C.ONC(C1C=C(NC(=O)NCC(C)C)SC=1)=N.ClCC(NO)=N>>[C:13]([O:12][C:11]([NH:10][C:7]1[N:35]([CH3:36])[N:69]=[CH:70][C:6]=1[C:5]([NH:44][OH:43])=[NH:87])=[O:17])([CH3:14])([CH3:15])[CH3:16]

Participants

12

Reactant 11

HCID 178425642HCID 178425642, compoundHCID 178434781HCID 178434781, compoundHCID 178435050HCID 178435050, compoundHCID 178438242HCID 178438242, compoundHCID 178449556HCID 178449556, compoundHCID 178452725HCID 178452725, compoundHCID 178452799HCID 178452799, compoundHCID 178452891HCID 178452891, compoundHCID 178452999HCID 178452999, compoundHCID 178477716HCID 178477716, compoundHCID 178511097HCID 178511097, compound

Product 1

HCID 178481840HCID 178481840, compound

Procedure

tert-Butyl [4-(N-Hydroxycarbamimidoyl)thiophen-2-yl]carbamate; tert-Butyl [5-(N-Hydroxycarbamimidoyl)-1-(2-trimethylsilylethoxymethyl)-1H-imidazol-4-yl]carbamate; tert-Butyl [4-(N-Hydroxycarbamimidoyl)-1-(2-trimethylsilylethoxymethyl)-1H-imidazol-5-yl]carbamate; tert-Butyl [4-(N-Hydroxycarbamimidoyl)-3-methylisoxazol-5-yl]carbamate; tert-Butyl [3-(N-Hydroxycarbamimidoyl)phenyl]carbamate; 3-Fluoro-N-hydroxy-4-methylbenzamidine; 2-Methyl-N-hydroxythiophene-3-carboxamidine; 2-Ethyl-N-hydroxythiophene-3-carboxamidine; 5-Ethanesulfonylamino-N-hydroxythiophene-3-carboxamidine; 3-[4-(N-Hydroxycarbamimidoyl)thiophen-2-yl]-1-isobutylurea; tert-butyl [5-(N-Hydroxycarbamimidoyl)-2-methylsulfanylthiazol-4-yl] carbamate; and 2-Chloro-N-hydroxyacetamidine.

Sources & evidence

ORD record
ord-a734220dd14d4703ac30ff63e708b109
Source dataset
uspto-grants-2005_08
Patent number
US06924284B2

Reaction notes

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