HCID 69792697, compound → HCID 69792524, compound

HRID 584271Notes

Reaction equation

HRID 584271 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[CH:10][C:11]([O:13]CC)=[O:12])=[CH:5][C:4]=1[C:16]1[C:25]([O:26][CH2:27][C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([O:34]COC)[CH:29]=2)=[CH:24][C:23]2[C:22]([CH3:39])([CH3:38])[CH2:21][CH2:20][C:19]([CH3:41])([CH3:40])[C:18]=2[CH:17]=1>C(O)C>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[CH:10][C:11]([OH:13])=[O:12])=[CH:5][C:4]=1[C:16]1[C:25]([O:26][CH2:27][C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([OH:34])[CH:29]=2)=[CH:24][C:23]2[C:22]([CH3:39])([CH3:38])[CH2:21][CH2:20][C:19]([CH3:41])([CH3:40])[C:18]=2[CH:17]=1

Participants

3

Reactant 1

HCID 69792697HCID 69792697, compound

Product 1

HCID 69792524HCID 69792524, compoundYield 83.4%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a manner similar to that of Example 2(g) but in ethanol as solvent, starting from 1.9 g (3.4 mmol) of ethyl 3-{4-methoxy-3-[3-(3-methoxymethoxybenzyloxy)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthyl]phenyl}acrylate obtained in Example 30(d), 1.38 g (79%) of the expected compound was obtained in the form of a white powder having a melting point of 131°-133° C.

Sources & evidence

ORD record
ord-929aca677d7049429d03769725ac91ff
Source dataset
uspto-grants-2005_08
Patent number
US06924388B2

Reaction notes

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