(3,5-Di-tert-butyl-2-propoxyphenyl)boronic acid → 3-(3',5'-di-tert-butyl-6-hydroxy-2'-propyloxy-3-biphenylyl)acrylic Acid

Participants

Reaction Steps

In a manner similar to that of Example 1(c), by reaction of 1.0 g (3.7 mmol) of ethyl 3-(3-bromo-4-hydroxyphenyl)acrylate obtained in Example 34(d) with 2.14 g (7.33 mmol) of 2-propyloxy-3,5-di-tert-butylphenylboronic acid obtained above, 70 mg (4%) of the expected compound were obtained in the form of a colorless oil.

Provenance & Evidence