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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 584278Generated: November 2, 2026

2-Butyloxy-3,5-di-tert-butylphenylboronic acid → 3-(3',5'-di-tert-butyl-6-hydroxy-2'-butyloxy-3-biphenylyl)acrylic Acid

https://huagongshe.com/reaction/584278

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Butyloxy-3,5-di-tert-butylphenylboronic acidHCID 22345412—
ReactantEthyl 3-(3-bromo-4-hydroxyphenyl)acrylateHCID 69793988—
Product3-(3',5'-di-tert-butyl-6-hydroxy-2'-butyloxy-3-biphenylyl)acrylic AcidHCID 697926887.2%

Reaction Steps

In a manner similar to that of Example 1(c), by reaction of 6.2 g (22.8 mmol) of ethyl 3-(3-bromo-4-hydroxyphenyl)acrylate obtained in Example 34(d) with 14 g (45.7 mmol) of 2-butyloxy-3,5-di-tert-butylphenylboronic acid obtained above, 700 mg (7%) of the expected compound were obtained in the form of a yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06924388B2
Source datasetuspto-grants-2005_08
ORD IDord-d2408ebf6a93473abdaef6bb431e74a4
Source noteuspto-grants-2005_08