反应详情

In a manner similar to that of Example 1(d), by reacting 27 g (135 mmol) of 3-bromo-4-ethylphenylamine with 11 g (162 mmol) of sodium nitrite, and after purification by chromatography on a column of silica eluted with a mixture of heptane and ethyl acetate (90/10), 13 g (49%) of the expected product are obtained in the form of a brown oil.

1. customafter purification by chromatography on a column of silica
2. washeluted with a mixture of heptane and ethyl acetate (90/10), 13 g (49%) of the expected product
3. customare obtained in the form of a brown oil