3,4-Bis(benzoyloxymethyl)benzyl bromide → 1-{5'-[3,4-Bis(benzoyloxymethyl)benzyloxy]-2,2'-diethylbiphenyl-4-yl}-1-propanone

Participants

Reaction Steps

In a manner similar to that of Example 1(o), by reacting 1.67 g (5.9 mmol) of 1-(2,2′-diethyl-5′-hydroxybiphenyl-4-yl)-1-propanone with 2.73 g (6.2 mmol) of 3,4-bis(benzoyloxymethyl)benzyl bromide, and after purification by chromatography on a column of silica eluted with a mixture of heptane and ethyl acetate (95/5), 1.88 g (50%) of the expected product are obtained in the form of an oil.

Provenance & Evidence