2-Isopropylphenol → HCID 22345593, compound
Reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[OH:10])([CH3:3])[CH3:2].[C:11](Cl)(=[O:14])[CH2:12][CH3:13]>>[OH:10][C:5]1[CH:6]=[CH:7][C:8]([C:11](=[O:14])[CH2:12][CH3:13])=[CH:9][C:4]=1[CH:1]([CH3:3])[CH3:2]Participants
3
Procedure
In a manner similar to that of Example 1(a), by reacting 10 g (73 mmol) of 2-isopropylphenol with 6.3 ml (73 mmol) of propionyl chloride, 4.5 g (32%) of the expected product are obtained in the form of white crystals with a melting point of 105° C.
Sources & evidence
- ORD record
- ord-a84b8035837a4a7fa00b825089ab1c09
- Source dataset
- uspto-grants-2005_08
- Patent number
- US06924400B2
Reaction notes
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