HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-(chloromethyl)benzene → 4-Chlorobenzyl-2,5-dimethylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-(chloromethyl)benzene | HCID 7723 | — |
| Reactant | 2,5-Dimethylpiperazine | HCID 7816 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Chlorobenzyl-2,5-dimethylpiperazine | HCID 22313576 | — |
Reaction Steps
Was synthesized in the same way as A) from 1-chloro-4-chloromethyl-benzene (1.27 g, 7.89 mmol) and 2,5-dimethyl-piperazine (1.0 g, 8.77 mmol) in DMF. Yield 701 mg, 37%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06927222B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-21933219291b4d68b705bdb246506ecd |
| Source note | uspto-grants-2005_08 |