HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Chlorophenoxy)pyrrolidine → 1-[3-(4-Chlorophenoxy)-1-pyrrolidinyl]-3-(5-methoxy-2-nitrophenoxy)-2-propanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Chlorophenoxy)pyrrolidine | HCID 12999570 | — |
| Reactant | 2-[(5-Methoxy-2-nitrophenoxy)methyl]oxirane | HCID 22313726 | — |
| Product | 1-[3-(4-Chlorophenoxy)-1-pyrrolidinyl]-3-(5-methoxy-2-nitrophenoxy)-2-propanol | HCID 22313604 | — |
Reaction Steps
The subtitle compound was prepared in analogy of Example 253 ii) from 2-[(5-methoxy-2-nitrophenoxy)methyl]oxirane (320 mg, 1.6 mmol) and 3-(4-chlorophenoxy)pyrrolidine (365 mg, 1.6 mmol). The crude product was obtained as a yellow oil (580 mg) and was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06927222B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-2caf0628d03c4c379cd257d76d55986c |
| Source note | uspto-grants-2005_08 |