HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 2,6,7-Trichloro-3-methylquinoxaline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 73148-15-9 | HCID 11064212 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | 2,6,7-Trichloro-3-methylquinoxaline | HCID 9794879 | — |
Reaction Steps
POCl3 was added to 6,7-Dichloro-3-methyl-1H-quinoxalin-2-one (10 g, 44 mmol) and 4-dimethylaminopyridine (1 g) and the mixture was refluxed for 0.5 hours. After cooling, the mixture was poured onto ice (500 ml), filtered and washed with water to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06927214B1 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-aa24519db1d843c2a38169ddc639d1c3 |
| Source note | uspto-grants-2005_08 |