Cesium carbonate → 2-[6,7-Dichloro-3-(methylsulfonyl)-2-quinoxalinyl]-4-phenylsemicarbazide

Participants

Reaction Steps

To a solution of 3,6,7-trichloro-2-(methylsulfonyl)quinoxaline (312 mg, 1.0 mmol) in DMF (10 ml) was added caesium carbonate (489 mg, 1.5 mmol) followed by 4-phenylsemicarbazide (182 mg, 1.2 mmol). The reaction was stirred overnight at room temperature. The product was purified by flash column chromatography using ethyl acetate:hexane 1:1 obtaining the title compound as a solid.

Provenance & Evidence