HuagongsheHuagongshe Chemistry Print Report · For research reference only
Difluoroacetic acid → HCID 60024125, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Difluoroacetic acid | HCID 9788 | — |
| Reactant | Lawesson's reagent | HCID 87949 | — |
| Reactant | HCID 60024140 | HCID 60024140 | — |
| Product | HCID 60024125 | HCID 60024125 | — |
Reaction Steps
Following the procedure described in Example 6 for the preparation of 13 the amine 27 (prepared according to the procedure described in U.S. Pat. No. 6,342,523) is first condensed with difluoroacetic acid and the resulting amide is allowed to react with Lawesson's Reagent to give the title compound 26 which is purified by silica gel chromatography with 5% MeOH—CH2Cl2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06927229B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-554c30dcafe64d26819b9f5ca2cd9e27 |
| Source note | uspto-grants-2005_08 |