HCID 2805345, compound → HCID 10269970, compound

HRID 584692Notes

Reaction equation

HRID 584692 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[N:7]([CH3:13])[C:8](Br)=[N:9][C:10]=1[CH3:11])=[O:5])[CH3:2].[C:14]([C:16]1[CH:17]=[C:18]([N:22]2[C:26]([CH3:27])=[CH:25][CH:24]=[C:23]2[CH3:28])[CH:19]=[CH:20][CH:21]=1)#[CH:15]>>[CH2:1]([O:3][C:4]([C:6]1[N:7]([CH3:13])[C:8]([C:15]#[C:14][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([N:22]3[C:26]([CH3:27])=[CH:25][CH:24]=[C:23]3[CH3:28])[CH:17]=2)=[N:9][C:10]=1[CH3:11])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 2805345HCID 2805345, compoundHCID 13897513ethyl 2-bromo-1,4-dimethyl-1H-imidazole-5-carboxylate

Product 1

HCID 10269970HCID 10269970, compound

Procedure

The title compound, MS: m/e=362.8 (M+H+), was prepared in accordance with the general method of example 1b from 2-bromo-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester and 1-(3-ethynyl-phenyl)-2,5-dimethyl-1H-pyrrole.

Sources & evidence

ORD record
ord-348bfcbaf8a44bb992bad80986c0fb3c
Source dataset
uspto-grants-2005_08
Patent number
US06927232B2

Reaction notes

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