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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 584702Generated: October 25, 2026

4-Ethynylaniline → 2-(4-Amino-phenylethynyl)-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester

https://huagongshe.com/reaction/584702

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-EthynylanilineHCID 3760025—
Reactantethyl 2-bromo-1,4-dimethyl-1H-imidazole-5-carboxylateHCID 13897513—
Product2-(4-Amino-phenylethynyl)-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl esterHCID 9835474—

Reaction Steps

The title compound, MS: m/e=284.4 (M+H+) was prepared in accordance with the general method of example 1b from 2-bromo-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester and 4-ethynylaniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06927232B2
Source datasetuspto-grants-2005_08
ORD IDord-4c43b0a6f56540e4b80544ccf17f1cb3
Source noteuspto-grants-2005_08