Potassium cyanate → HCID 22341576, compound

HRID 584745Notes

Reaction equation

HRID 584745 reaction equation
[O-:1][C:2]#[N:3].[K+].Cl.Cl.[NH:7]([C:9]1[CH:10]=[CH:11][C:12]([O:15][CH3:16])=[N:13][CH:14]=1)[NH2:8]>O>[CH3:16][O:15][C:12]1[N:13]=[CH:14][C:9]([NH:7][NH:8][C:2]([NH2:3])=[O:1])=[CH:10][CH:11]=1

Participants

4

Reactant 2

HCID 11378442Potassium cyanateHCID 22341572(6-Methoxy-pyridin-3-yl)-hydrazine dihydrochloride

Product 1

HCID 22341576HCID 22341576, compoundYield 148%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Potassium cyanate (8.41 g, 104 mmol) was added to a solution of 5-hydrazino-2-methoxypyridine dihydrochloride (20 g, 94.3 mmol) in water (200 mL). The mixture was stirred for 2 hour and adjusted pH to 7. The solvent was removed under reduced pressure and obtained crude powder to give 2-(6-methoxypyridin-3-yl)hydrazinecarboxamide. (25.4 g, 148% yield).

Workup

  1. customThe solvent was removed under reduced pressure
  2. customobtained crude powder

Sources & evidence

ORD record
ord-ef8da6f1c6214a15b6b493085b188973
Source dataset
uspto-grants-2005_08
Patent number
US06927230B2

Reaction notes

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