2-chloro-N,N-dimethylacetamide → HCID 10293252, compound

HRID 584753Notes

Reaction equation

HRID 584753 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=3)=[N:12][C:11]([OH:22])=[N:10]2)=[CH:5][CH:4]=1.Cl[CH2:24][C:25]([N:27]([CH3:29])[CH3:28])=[O:26]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=3)=[N:12][C:11]([O:22][CH2:24][C:25]([N:27]([CH3:29])[CH3:28])=[O:26])=[N:10]2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 758862-chloro-N,N-dimethylacetamideHCID 1784890151,5-bis(4-methoxyphenyl)-1H-1,2,4-triazol-3-ol

Product 1

HCID 10293252HCID 10293252, compoundYield 72.6%

Procedure

2-{[1,5-bis(4-methoxyphenyl)-1H-1,2,4-triazol-3-yl]oxy}-N,N-dimethylacetamide (467 mg, 72.6% yield) was prepared from 1,5-bis(4-methoxyphenyl)-1H-1,2,4-triazol-3-ol and 2-chloro-N,N-dimethylacetamide by the similar manner described for Example 18.

Sources & evidence

ORD record
ord-767ad8e914e8425d9194f59d4f4c16ec
Source dataset
uspto-grants-2005_08
Patent number
US06927230B2

Reaction notes

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