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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 584817Generated: October 31, 2026

HCID 22249494, compound → HCID 22249612, compound

https://huagongshe.com/reaction/584817

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22249494HCID 22249494—
CatalystHCID 178418406HCID 178418406—
SolventTolueneHCID 1140—
SolventDichloromethaneHCID 6344—
ProductHCID 22249612HCID 2224961284.6%

Reaction Steps

Activated manganese dioxide (45 mg, 0.51 mmol) was added to a solution of 1-(1-ethylpropyl)-7-iodo-4-mesityl-2,3-dihydro-1H-pyrrolo[3,2-c]quinoline (39 mg, 0.10 mmol) in toluene (4.0 mL) and methylene chloride (4.0 mL), followed by heating under reflux for one day. The mixture was filtered through Celite and evaporated, to give the title compound (32 mg) as pale yellow crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06927221B2
Source datasetuspto-grants-2005_08
ORD IDord-264c14b70b4942d299a4025eda4545d1
Source noteuspto-grants-2005_08