Thiazolidinedione → HCID 90847266, compound

HRID 584896Notes

Reaction equation

HRID 584896 reaction equation
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][NH:16][C:17](=[O:24])[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH:10]=2)=[CH:5][CH:4]=1)=O.[S:25]1[CH2:29][C:28](=[O:30])[NH:27][C:26]1=[O:31]>>[O:31]=[C:26]1[NH:27][C:28](=[O:30])[C:29](=[CH:1][C:3]2[CH:4]=[CH:5][C:6]([C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][NH:16][C:17](=[O:24])[C:18]4[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=4)[CH:10]=3)=[CH:7][CH:8]=2)[S:25]1

Participants

3

Reactant 2

HCID 5437ThiazolidinedioneHCID 22341436HCID 22341436, compound

Product 1

HCID 90847266HCID 90847266, compoundYield 93%

Procedure

In a manner similar to that of Example 1(f), by reacting 1 g (3.2 mmol) of N-(4′-formylbiphenyl-3-ylmethyl)benzamide with 370 mg (3.2 mmol) of 2,4-thiazolidine dione, 1.2 g (93%) of expected product are obtained.

Sources & evidence

ORD record
ord-bec3c62f02d240d88759e9731464653a
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

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