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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 584906Generated: October 27, 2026

Thiazolidinedione → Tert-butyl [4'-(2,4-dioxothiazolidin-5-ylidenemethyl)biphenyl-3-ylmethyl]methylcarbamate

https://huagongshe.com/reaction/584906

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiazolidinedioneHCID 5437—
ReactantTert-butyl (4'-formylbiphenyl-3-ylmethyl)methylcarbamateHCID 86591268—
ProductTert-butyl [4'-(2,4-dioxothiazolidin-5-ylidenemethyl)biphenyl-3-ylmethyl]methylcarbamateHCID 8659893881%

Reaction Steps

In a manner similar to that of Example 1(f), by reacting 8 g (25 mmol) of tert-butyl (4′-formyl-biphenyl-3-ylmethyl)methylcarbamate with 2.9 g (25 mmol) of 2,4-thiazolidine dione, 8.6 g (81%) of the expected product are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06927228B2
Source datasetuspto-grants-2005_08
ORD IDord-cecb532f2fc747c0a68a21c41568d842
Source noteuspto-grants-2005_08