4-Formylphenylboronic Acid → HCID 22341436, compound

HRID 584917Notes

Reaction equation

HRID 584917 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][CH:17]=1)[CH2:5][NH:6][C:7](=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[CH:18]([C:20]1[CH:25]=[CH:24][C:23](B(O)O)=[CH:22][CH:21]=1)=[O:19]>>[CH:18]([C:20]1[CH:25]=[CH:24][C:23]([C:2]2[CH:17]=[CH:16][CH:15]=[C:4]([CH2:5][NH:6][C:7](=[O:14])[C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:3]=2)=[CH:22][CH:21]=1)=[O:19]

Participants

3

Reactant 2

HCID 5910734-Formylphenylboronic AcidHCID 22341452HCID 22341452, compound

Product 1

HCID 22341436HCID 22341436, compoundYield 50%

Procedure

In a manner similar to that of Example 1(e), by reacting 7.4 g (25.4 mmol) of N-(3-bromo benzyl)-benzamide with 5.7 g (38.2 mmol) of 4-formylbenzene-boronic acid, 4 g (50%) of the expected product are obtained.

Sources & evidence

ORD record
ord-08bd9502717645bcab45818a64817e67
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

Loading…