Thiazolidinedione → HCID 86591252, compound

HRID 584924Notes

Reaction equation

HRID 584924 reaction equation
[CH2:1]([N:3]([CH2:11][C:12]1[CH:13]=[C:14]([C:18]2[CH:23]=[CH:22][C:21]([CH:24]=O)=[CH:20][CH:19]=2)[CH:15]=[CH:16][CH:17]=1)[C:4](=[O:10])[O:5][C:6]([CH3:9])([CH3:8])[CH3:7])[CH3:2].[S:26]1[CH2:30][C:29](=[O:31])[NH:28][C:27]1=[O:32]>>[O:32]=[C:27]1[NH:28][C:29](=[O:31])[C:30](=[CH:24][C:21]2[CH:20]=[CH:19][C:18]([C:14]3[CH:15]=[CH:16][CH:17]=[C:12]([CH2:11][N:3]([CH2:1][CH3:2])[C:4](=[O:10])[O:5][C:6]([CH3:7])([CH3:9])[CH3:8])[CH:13]=3)=[CH:23][CH:22]=2)[S:26]1

Participants

3

Reactant 2

HCID 5437ThiazolidinedioneHCID 86591251HCID 86591251, compound

Product 1

HCID 86591252HCID 86591252, compoundYield 92%

Procedure

In a manner similar to that of Example 1(f), by reacting 1.35 g (4 mmol) of tert-butyl ethyl(4′-formylbiphenyl-3-ylmethyl)carbamate with 470 mg (4 mmol) of 2,4-thiazolidine dione, 1.6 g (92%) of the expected product are obtained.

Sources & evidence

ORD record
ord-4e45b9c17ce346cbbd77620e46d07e79
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

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