Thiazolidinedione → HCID 91327494, compound

HRID 584933Notes

Reaction equation

HRID 584933 reaction equation
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:10]=2)=[CH:5][CH:4]=1)=O.[S:20]1[CH2:24][C:23](=[O:25])[NH:22][C:21]1=[O:26]>>[O:26]=[C:21]1[NH:22][C:23](=[O:25])[C:24](=[CH:1][C:3]2[CH:8]=[CH:7][C:6]([C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:10]=3)=[CH:5][CH:4]=2)[S:20]1

Participants

3

Reactant 2

HCID 5437ThiazolidinedioneHCID 15382496HCID 15382496, compound

Product 1

HCID 91327494HCID 91327494, compoundYield 83%

Procedure

In a manner similar to that of Example 1(f), by reacting 11.7 g (46 mmol) of ethyl 4′-formylbiphenyl-3-carboxylate with 5.4 g (46 mmol) of 2,4-thiazolidine dione, 13 g (83%) of the expected product are obtained.

Sources & evidence

ORD record
ord-30d1f69ec8bd43688002362db19fa04b
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

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