4-Formylphenylboronic Acid → HCID 22341535, compound

HRID 584941Notes

Reaction equation

HRID 584941 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][CH:20]=1)[CH2:5][N:6]([CH2:15][CH2:16][CH3:17])[C:7](=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[CH:21]([C:23]1[CH:28]=[CH:27][C:26](B(O)O)=[CH:25][CH:24]=1)=[O:22]>>[CH:21]([C:23]1[CH:28]=[CH:27][C:26]([C:2]2[CH:20]=[CH:19][CH:18]=[C:4]([CH2:5][N:6]([CH2:15][CH2:16][CH3:17])[C:7](=[O:14])[C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:3]=2)=[CH:25][CH:24]=1)=[O:22]

Participants

3

Reactant 2

HCID 5910734-Formylphenylboronic AcidHCID 22341470HCID 22341470, compound

Product 1

HCID 22341535HCID 22341535, compoundYield 53%

Procedure

In a manner similar to that of Example 1(e), by reacting 1.4 g (4.2 mmol) of N-(3-bromo benzyl)-N-propylbenzamide with 940 mg (6.2 mmol) of 4-formylbenzene boronic acid, 780 mg (53%) of the expected product are obtained.

Sources & evidence

ORD record
ord-5e224885c8044231ac68f23e77a80db6
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

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