Thiazolidinedione → HCID 86591259, compound

HRID 584943Notes

Reaction equation

HRID 584943 reaction equation
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([NH:15][C:16](=[O:22])[O:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH:10]=2)=[CH:5][CH:4]=1)=O.[S:23]1[CH2:27][C:26](=[O:28])[NH:25][C:24]1=[O:29]>>[O:29]=[C:24]1[NH:25][C:26](=[O:28])[C:27](=[CH:1][C:3]2[CH:8]=[CH:7][C:6]([C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([NH:15][C:16](=[O:22])[O:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH:10]=3)=[CH:5][CH:4]=2)[S:23]1

Participants

3

Reactant 2

HCID 5437ThiazolidinedioneHCID 86591258HCID 86591258, compound

Product 1

HCID 86591259HCID 86591259, compoundYield 100.1%

Procedure

In a manner similar to that of Example 1(f), by reacting 9.5 g (32 mmol) of tert-butyl (4′-formyl-biphenyl-3-yl)carbamate with 3.8 g (32 mmol) of 2,4-thiazolidine dione, 12.7 g (91%) of the expected product are obtained.

Sources & evidence

ORD record
ord-7cfe653b08dc4d2c9deb55f0610a9c28
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

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