HCID 86591260, compound → HCID 22341398, compound

HRID 584945Notes

Reaction equation

HRID 584945 reaction equation
[O:1]=[C:2]1[NH:6][C:5](=[O:7])[C:4](=[CH:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH2:21][N:22]([CH3:37])[C:23](=[O:36])[C:24]4[CH:29]=[CH:28][C:27]([O:30][CH2:31][CH3:32])=[C:26]([O:33][CH2:34][CH3:35])[CH:25]=4)[CH:16]=3)=[CH:11][CH:10]=2)[S:3]1>CO>[O:1]=[C:2]1[NH:6][C:5](=[O:7])[CH:4]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH2:21][N:22]([CH3:37])[C:23](=[O:36])[C:24]4[CH:29]=[CH:28][C:27]([O:30][CH2:31][CH3:32])=[C:26]([O:33][CH2:34][CH3:35])[CH:25]=4)[CH:16]=3)=[CH:11][CH:10]=2)[S:3]1

Participants

3

Reactant 1

HCID 86591260HCID 86591260, compound

Product 1

HCID 22341398HCID 22341398, compoundYield 41.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a manner similar to that of Example 1(g), starting with 360 mg (0.7 mmol) of N-[4′-(2,4-dioxothiazolidin-5-ylidenemethyl)biphenyl-3-ylmethyl]-3,4-diethoxy-N-methylbenzamide in 15 ml of methanol, 150 mg (40%) of the desired product, with a melting point of 66° C., are obtained.

Sources & evidence

ORD record
ord-3031feaf12804714b7115095ff08ae24
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

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