HCID 86591266, compound → HCID 9846696, compound

HRID 584953Notes

Reaction equation

HRID 584953 reaction equation
[O:1]=[C:2]1[NH:6][C:5](=[O:7])[C:4](=[CH:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH2:21][N:22]([CH3:32])[C:23](=[O:31])[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH:16]=3)=[CH:11][CH:10]=2)[S:3]1>O1CCOCC1>[O:1]=[C:2]1[NH:6][C:5](=[O:7])[CH:4]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH2:21][N:22]([CH3:32])[C:23](=[O:31])[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH:16]=3)=[CH:11][CH:10]=2)[S:3]1

Participants

3

Reactant 1

HCID 86591266HCID 86591266, compound

Product 1

HCID 9846696HCID 9846696, compoundYield 53%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

In a manner similar to that of Example 1(g), starting with 220 mg (0.5 mmol) of N-[4′-(2,4-dioxothiazolidin-5-ylidenemethyl)biphenyl-3-ylmethyl]-N-methyloctanamide in 10 ml of dioxane, 120 mg (53%) of the desired product, with a melting point of 36° C., are obtained.

Sources & evidence

ORD record
ord-7b295e24072c4331bb0437ec3bf90760
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

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