4-(Dimethylamino)benzoyl chloride → HCID 10116297, compound

Participants

Reaction Steps

In a manner similar to that of Example 37(e), by reacting 1 g (2.2 mmol) of 5-(3′-methylaminomethyl-biphenyl-4-ylmethyl)thiazolidine-2,4-dione trifluoro-acetate with 500 mg (3 mmol) of 4-dimethylaminobenzoyl chloride, and after purification, 200 mg (20%) of 4-dimethylamino-N-[4′-(2,4-dioxothiazolidin-5-ylmethyl)-biphenyl-3-ylmethyl]-N-methylbenzamide, with a melting point of 100° C., are obtained.

Provenance & Evidence