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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 584981Generated: October 26, 2026

Thiazolidinedione → 5-(3'-Methylaminobiphenyl-4-ylmethylene)thiazolidine-2,4-dione

https://huagongshe.com/reaction/584981

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiazolidinedioneHCID 5437—
Reactant3'-Methylaminobiphenyl-4-carbaldehydeHCID 1394524—
Product5-(3'-Methylaminobiphenyl-4-ylmethylene)thiazolidine-2,4-dioneHCID 8659894191.7%

Reaction Steps

In a manner similar to that of Example 1(f), starting with 2.9 g (13.7 mmol) of 3′-methylaminobiphenyl-4-carboxaldehyde and 1.6 g (13.7 mmol) of 2,4-thiazolidine dione, 3.9 g (91%) of the expected product are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06927228B2
Source datasetuspto-grants-2005_08
ORD IDord-1b9881585c8f4effb24e41666e74170b
Source noteuspto-grants-2005_08