Phenylacetyl chloride → n-[4'-(2,4-Dioxothiazolidin-5-ylidenemethyl)-biphenyl-3-yl]-n-methyl-2-phenylacetamide

Participants

Reaction Steps

In a manner similar to that of Example 37(e), by reacting 1 g (3.2 mmol) of 5-(3′-methylaminobiphenyl-4-ylmethylene)thiazolidine-2,4,dione with 470 μl (3.5 mmol) of phenylacetyl chloride, and after purification, 1.4 g (50%) of N-[4′-(2,4-dioxothiazolidin-5-ylidenemethyl)biphenyl-3-yl]-N-methyl-2-phenylacetamide are obtained.

Provenance & Evidence