Thiazolidinedione → HCID 73884093, compound

HRID 584986Notes

Reaction equation

HRID 584986 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[CH:12][C:11]([CH:14]=O)=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[S:16]1[CH2:20][C:19](=[O:21])[NH:18][C:17]1=[O:22]>>[OH:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:9]=[CH:10][C:11]([CH:14]=[C:20]3[S:16][C:17](=[O:22])[NH:18][C:19]3=[O:21])=[CH:12][CH:13]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 5437ThiazolidinedioneHCID 27592964-(3-hydroxyphenyl)benzaldehyde

Product 1

HCID 73884093HCID 73884093, compoundYield 100%

Procedure

In a manner similar to that of Example 1(f), starting with 15 g (75.7 mmol) of 3′-hydroxybiphenyl-4-carbaldehyde and 8.85 g (75.7 mmol) of 2,4-thiazolidine dione, 22.5 g (100%) of the expected product are obtained.

Sources & evidence

ORD record
ord-b358ccc3916e40a086f2cf84dadf3f1b
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

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