Thiazolidinedione → HCID 86591271, compound

HRID 584991Notes

Reaction equation

[CH2:1]([O:8][C:9]1[C:14]([C:15]2[CH:20]=[CH:19][C:18]([CH:21]=O)=[CH:17][CH:16]=2)=[CH:13][C:12]([CH2:23][N:24]([CH3:34])[C:25](=[O:33])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:35]1[CH2:39][C:38](=[O:40])[NH:37][C:36]1=[O:41]>>[CH2:1]([O:8][C:9]1[C:14]([C:15]2[CH:16]=[CH:17][C:18]([CH:21]=[C:39]3[S:35][C:36](=[O:41])[NH:37][C:38]3=[O:40])=[CH:19][CH:20]=2)=[CH:13][C:12]([CH2:23][N:24]([CH3:34])[C:25](=[O:33])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])=[CH:11][CH:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 5437Thiazolidinedione

HCID 22341400HCID 22341400, compound

Product 1

HCID 86591271HCID 86591271, compound

Procedure

In a manner similar to that of Example 1(f), by reacting 11.5 g (22 mmol) of N-(6-benzyloxy-4′-formylbiphenyl-3-ylmethyl)-N-methyloctanamide and 2.5 g (22 mmol) of 2,4-thiazolidine dione, the expected product is obtained in the form of a pale yellow powder with a melting point of 162° C.

Sources & evidence

ORD record: ord-fc61cbc1885041d48657af89bd94ae1b
Source dataset: uspto-grants-2005_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06927228B2

Reaction notes

Loading…