1,4-Dioxane → HCID 10303068, compound

Participants

Reaction Steps

In a manner similar to that of Example 1(g), starting with 1 g (1.8 mmol) of N-[6-benzyloxy-4′-(2,4-dioxothiazolidin-5-ylidenemethyl)biphenyl-3-ylmethyl]-N-methyloctanamide (obtained in Example 75) in ml of dioxane and 1 ml of triethylamine under 3 atm of hydrogen, 270 mg (27%) of the expected product are obtained in the form of a yellow oil.

Provenance & Evidence