反应详情

In a manner similar to that of Example 1(e), by reacting 8 g (18.5 mmol) of N-(2-benzyloxy-5-bromo benzyl)-N-methyloctanamide and 3.6 g (24 mmol) of 4-formylbenzene boronic acid, and after purification by chromatography on a column of silica eluted with a heptane/ethyl acetate mixture (8/2), 5.8 g (69%) of the expected product are obtained in the form of a white solid.

1. customafter purification by chromatography on a column of silica
2. washeluted with a heptane/ethyl acetate mixture (8/2), 5.8 g (69%) of the expected product
3. customare obtained in the form of a white solid