4-Formylphenylboronic Acid → HCID 22341484, compound

HRID 585000Notes

Reaction equation

HRID 585000 reaction equation
Br[C:2]1[CH:3]=[C:4]([C:14]([NH:16][CH3:17])=[O:15])[CH:5]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:7]=1.[CH:18]([C:20]1[CH:25]=[CH:24][C:23](B(O)O)=[CH:22][CH:21]=1)=[O:19]>>[CH:18]([C:20]1[CH:25]=[CH:24][C:23]([C:2]2[CH:7]=[C:6]([C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:5]=[C:4]([C:14]([NH:16][CH3:17])=[O:15])[CH:3]=2)=[CH:22][CH:21]=1)=[O:19]

Participants

3

Reactant 2

HCID 5910734-Formylphenylboronic AcidHCID 22341539HCID 22341539, compound

Product 1

HCID 22341484HCID 22341484, compound

Procedure

In a manner similar to that of Example 1(e), by reacting 2 g (7 mmol) of 5-bromo-N-methyl-3-biphenylcarboxamide and 1.4 g (9.3 mmol) of 4-formylbenzene boronic acid, and after purification by recrystallization from acetonitrile, 1.4 g (63%) of the expected product are obtained in the form of a beige-colored solid.

Workup

  1. customafter purification
  2. customby recrystallization from acetonitrile, 1.4 g (63%) of the expected product
  3. customare obtained in the form of a beige-colored solid

Sources & evidence

ORD record
ord-69759b1725f74503a25dcf1191cfb327
Source dataset
uspto-grants-2005_08
Patent number
US06927228B2

Reaction notes

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