HCID 86591272, compound → HCID 22341409, compound

Participants

Reaction Steps

In a manner similar to that of Example 1(g), starting with 370 mg (7 mmol) of N-[4″-(2,4-dioxothiazolidin-5-ylidene-methyl)[1,1′;3′,1″]terphenyl-5′-ylmethyl]-N-methyl-octanamide in 5 ml of dioxane and under 3 atm of hydrogen, and after purification by chromatography on a column of silica eluted with a heptane/ethyl acetate mixture (6/4), 170 mg (47%) of N-[4″-(2,4-dioxo-thiazolidin-5-ylmethyl)[1,1′;3′,1″]terphenyl-5′-yl-methyl]-N-methyloctanamide are obtained in the form of a pale yellow foam.

Provenance & Evidence