反应详情

In a manner similar to that of Example 1(e), by reacting 38 g (127 mmol) of tert-butyl (3-bromo benzyl)-N-methylcarbamate obtained in Example 79(b) with 25.6 g (170 mmol) of 4-formylbenzene boronic acid, and after purification by chromatography on a column of silica eluted with a heptane/ethyl acetate mixture (9/1), 20 g (57%) of the expected product are obtained.

1. customafter purification by chromatography on a column of silica
2. washeluted with a heptane/ethyl acetate mixture (9/1), 20 g (57%) of the expected product
3. customare obtained