Thiazolidinedione → HCID 73884095, compound

HRID 585011Notes

Reaction equation

[CH2:1]([NH:3][C:4]1[CH:5]=[C:6]([C:10]2[CH:15]=[CH:14][C:13]([CH:16]=O)=[CH:12][CH:11]=2)[CH:7]=[CH:8][CH:9]=1)[CH3:2].[S:18]1[CH2:22][C:21](=[O:23])[NH:20][C:19]1=[O:24]>>[CH2:1]([NH:3][C:4]1[CH:5]=[C:6]([C:10]2[CH:11]=[CH:12][C:13]([CH:16]=[C:22]3[S:18][C:19](=[O:24])[NH:20][C:21]3=[O:23])=[CH:14][CH:15]=2)[CH:7]=[CH:8][CH:9]=1)[CH3:2]

Participants

Reactant 2

HCID 5437Thiazolidinedione

HCID 22341507HCID 22341507, compound

Product 1

HCID 73884095HCID 73884095, compoundYield 77.1%

Procedure

In a manner similar to that of Example 1(f), by reacting 900 mg (4 mmol) of 3′-ethylaminobiphenyl-4-carbaldehyde with 470 mg (4 mmol) of 2,4-thiazolidine dione, 1 g (77%) of the expected product are obtained in the form of an orange solid.

Sources & evidence

ORD record: ord-1d2b02be871248688f270b17a85d8185
Source dataset: uspto-grants-2005_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06927228B2

Reaction notes

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