Water → HCID 22340242, compound

Participants

Reaction Steps

45 g (0.123 moles) of the compound having formula (XIV) obtained as described in the previous step (b), dissolved in 50 ml of methanol, are added to the suspension thus obtained. The reaction mixture is then left under stirring at room temperature for 18 hours and is subsequently hydrolyzed with water and extracted with various portions of ethyl ether. The ether extracts are joined, anhydrified on Na2SO4 and concentrated by evaporation at reduced pressure, obtaining at the end an oily red residue containing 43.5 g of the desired product having formula (XV) (65% purity upon GC analysis, 86% yield). Analyses show that both ethyl ester (45%) and methyl ester (55%) deriving from the transesterification of the product (XV) due to the use of methanol as solvent, are present. The product is not additionally purified.

Provenance & Evidence