3-(4-Hydroxyphenyl)-2-methyl-2-(4-tert-butylphenoxy)-propionic acid ethyl ester → HCID 22339969, compound

HRID 585204Notes

Reaction equation

HRID 585204 reaction equation
C([O:3][C:4](=[O:26])[C:5]([CH3:25])([O:14][C:15]1[CH:20]=[CH:19][C:18]([C:21]([CH3:24])([CH3:23])[CH3:22])=[CH:17][CH:16]=1)[CH2:6][C:7]1[CH:12]=[CH:11][C:10](O)=[CH:9][CH:8]=1)C.[CH3:27][C:28]1[O:32][C:31]([C:33]2[S:34][CH:35]=[CH:36][CH:37]=2)=[N:30][C:29]=1[CH2:38][CH2:39][O:40]S(C1C=CC(C)=CC=1)(=O)=O>>[CH3:25][C:5]([O:14][C:15]1[CH:16]=[CH:17][C:18]([C:21]([CH3:24])([CH3:23])[CH3:22])=[CH:19][CH:20]=1)([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:40][CH2:39][CH2:38][C:29]2[N:30]=[C:31]([C:33]3[S:34][CH:35]=[CH:36][CH:37]=3)[O:32][C:28]=2[CH3:27])=[CH:9][CH:8]=1)[C:4]([OH:26])=[O:3]

Participants

3

Reactant 2

HCID 208231563-(4-Hydroxyphenyl)-2-methyl-2-(4-tert-butylphenoxy)-propionic acid ethyl esterHCID 223400422-(5-Methyl-2-thiophen-2-yloxazol-4-yl)ethyl tosylate

Product 1

HCID 22339969HCID 22339969, compound

Procedure

The title compound was prepared, according to the procedure of Example 16, Step C, using 3-(4-hydroxyphenyl)-2-methyl-2-(4-tert-butylphenoxy)-propionic acid ethyl ester and toluene-4-sulfonic acid 2-(5-methyl-2-thiophen-2-yloxazol-4-yl)-ethyl ester to produce a white solid (19%). MS [EI+] 520 (M+H)+, [EI−] 518 (M−H)+.

Sources & evidence

ORD record
ord-db1c07e160e44d98abdd8b075f6d0773
Source dataset
uspto-grants-2005_08
Patent number
US06930120B2

Reaction notes

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