HRID585240

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1ccc(S(=O)(=O)OCCc2nc(-c3ccccc3)oc2C)cc1

HCID12051739

未命名化合物

结构：CCOC(=O)C(C)(Cc1ccc(O)cc1)Oc1ccc(F)cc1

HCID69316070

未命名化合物

PRODUCTS

生成物

结构：Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(C)(Oc2ccc(F)cc2)C(=O)O)cc1

HCID22339994

2-(4-Fluoro-phenoxy)-2-methyl-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic Acid

C28H26FNO5

PROCEDURE

实验过程

Standard Procedure (B) was utilized to prepare the title compound from 2-(4-fluorophenoxy)-3-(4-hydroxy-phenyl)-2-methyl-propionic acid ethyl ester and toluene-4-sulfonic acid 2-(2-phenyl-5-methyl-oxazol-4-yl)-ethyl ester. 1H NMR (400 MHz, CDCl3) δ 8.00-7.97 (m, 2H), 7.43-7.41 (m, 3H), 7.18 (d, 2H, J=8.99 Hz), 6.93-6.82 (m, 6H), 4.21 (t, 2H, J=6.65 Hz), 3.21 (d, 1H, J=14.08 Hz), 3.13 (d, 1H, J=14.08 Hz), 3.01 (t, 2H, J=6.65 Hz), 2.39 (s, 3H), 1.36 (s, 3H); HRMS (ES+) m/z exact mass calcd for C28H27NO5F 476.1873, found 476.1871.