HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → 1-Nitro-2,5-bis(trifluoromethyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | 1,4-Bis(trifluoromethyl)benzene | HCID 67945 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 1-Nitro-2,5-bis(trifluoromethyl)benzene | HCID 2734048 | 35% |
Reaction Steps
A process of nitrating 1,4-bis(trifluoromethyl)benzene by means of 100 mass % nitric acid at from 90 to 105° C. by using 24% fuming sulfuric acid as a solvent to obtain 2,5-bis(trifluoromethyl)nitrobenzene in a yield of 35% (J. Amer. Chem. Soc., 75, 4967 (1953)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06930214B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-a644530108b94ad983475f442eb57f48 |
| Source note | uspto-grants-2005_08 |