Indoline → 4-(2,3-dihydro-1H-indol-1-yl)-1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydroquinoline

Participants

Reaction Steps

Starting with 1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydro-4-quinolinol (390 mg, 1.19 mmol) prepared in Reference Example 2 and indoline (425 mg, 3.57 mmol), the same procedure as shown in Example 1 was repeated to give the product of interest, i.e., 4-(2,3-dihydro-1H-indol-1-yl)-1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydroquinoline (268 mg, yield: 54%) as a white crystal.

Provenance & Evidence