HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxybenzoic Acid → 1-(3-Methoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxybenzoic Acid | HCID 11461 | — |
| Reactant | 1,2,3,4-Tetrahydro-2-methyl-4-quinolinol | HCID 147634 | — |
| Product | 1-(3-Methoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol | HCID 22339232 | 27% |
Reaction Steps
Starting with 2-methyl-1,2,3,4-tetrahydro-4-quinolinol (3.00 g, 18.3 mmol) synthesized in the published manner and 3-methoxybenzoic acid (3.34 g, 22.0 mmol), the same procedure as shown in Reference Example 19 was repeated to give the titled compound (1.45 g, yield: 27%) as a white crystal. (cis:trans=1:1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06930104B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-5b593778956443bd8eafd7c9b3e79dea |
| Source note | uspto-grants-2005_08 |