HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,5-Trimethoxybenzoic Acid → 1-(3,4,5-Trimethoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,5-Trimethoxybenzoic Acid | HCID 8357 | — |
| Reactant | 1,2,3,4-Tetrahydro-2-methyl-4-quinolinol | HCID 147634 | — |
| Product | 1-(3,4,5-Trimethoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol | HCID 22339230 | 33.4% |
Reaction Steps
Starting with 2-methyl-1,2,3,4-tetrahydro-4-quinolinol (3.00 g, 18.3 mmol) synthesized in the published manner and 3,4,5-trimethoxybenzoic acid (2.0 g, 10.9 mmol), the same procedure as shown in Reference Example 19 was repeated to give the titled compound (1.30 g, yield: 33%) as a white crystal. (cis:trans=1:1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06930104B2 |
| Source dataset | uspto-grants-2005_08 |
| ORD ID | ord-91dad63fa1104a4b976fec8693f72513 |
| Source note | uspto-grants-2005_08 |