2,3,4,5-tetrahydro-1H-1-benzazepine → 1-(3,4-Dimethoxybenzoyl)-2-methyl-4-(2,3,4,5-tetrahydro-1H-benzazepin-1-yl)-1,2,3,4-tetrahydroquinoline

Participants

Reaction Steps

Starting with cis-1-(3,4-dimethoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinol (280 mg, 0.82 mmol) prepared in Reference Example 1 and 2,3,4,5-tetrahydro-1H-1-benzazepine (362 mg, 2.46 mmol), the same procedure as shown in Example 1 was repeated to give the titled compound (32 mg, yield: 9%) as a colorless oil. (cis:trans=1:1.5)

Provenance & Evidence